Biologics Drug Development
& Manufacturing

Accelerate your path to market with our range of advanced biologic services & technologies that help move your drug candidate forward.

We are a fully integrated biologics CDMO + CRO offering innovative drug development and manufacturing services, and technology solutions that move medicines forward.

Contact Us

Drug candidates in the biologics development pipeline are increasingly innovative. They are also more complex. As a highly specialized, leading complex biologics CDMO, Abzena have the experience to accelerate your path to the clinic or commercialization for mammalian, microbial, and bioconjugate modalities.

Through our complex chemistry expertise and seamless technology solutions, we provide comprehensive support from antibody discovery and developability, lead selection and optimization, through to commercial manufacturing for biologic drug candidates.

Fully integrated support across multiple modalities

We deliver end-to-end solutions for:

  • Monoclonal Antibodies (mAbs)
  • Antibody-Drug Conjugates (ADCs)
  • Antibody-Oligonucleotide Conjugates (AOCs)
  • Radionuclide Antibody-Conjugates (RACs) & Radionuclide Drug-Conjugates (RDCs)
  • Bispecific Antibodies (bsAbs)
  • Fusion Proteins
  • Cytokines
  • Recombinant & Conjugate Vaccines
  • Nanoparticles
  • Biosimilars

Biologics Services

We focus and collaborate with you on streamlining biologics development and manufacturing programs. We de-risk and challenge outdated assumptions. We do what is best for your biologics program to move forwards.

Antibody Discovery

Our antibody discovery experts specialize in building the tight foundations for your program. We look to start smart, setting you off on the optimal path to success.

Antibody Design & Protein Engineering

We offer a comprehensive antibody and protein engineering services including; hybridoma sequencing, microbial and mammalian production, antibody humanization and affinity maturation, protein deimmunization, biophysical characterization and custom engineering solutions.

Antibody Development

Our antibody development services ensure the candidates you take forward have reduced liabilities and a de-risked development path.

Analytics & Bioassays

Our approach to Analytics and Bioassays focuses on giving you the rapid insight to make informed decisions during your drug development journey. You can benefit from a wealth of experience across a diverse range of modalities including bioconjugates & ADCs, multi-specifics, fusions, fragments, agonist, and antagonist activities.

We apply over 20+ years of analytical experience and know-how to develop phase appropriate analytical methods necessary to produce high-quality, well-characterized material. We give you the data to support successful IND and marketing applications as you move your biologic program forwards to commercialization.

Immunogenicity Assays

Immunogenicity assays are an integral service to biologic drug development. Why? Because biotherapeutics, such as antibodies and proteins, to name but a few, can induce an immune response in the body which leads to the development of anti-drug antibodies (ADAs). At Abzena, we recognize the evaluation of a drug candidate’s developability is a pivotal early stage and have over 20 years of immunogenicity assay experience.

Cell Line Development (CLD)

We have developed multiple cell lines that have progressed from process development into manufacture and through clinical trials. Our cell line development (CLD) team has expressed biologics including antibodies, antibody fragments, bispecific antibodies, fusion proteins, growth factors and vaccines.

Formulation Development

Our formulation development experts align your drug to your preferred target product profile (TPP) with a comprehensive range of packages including stable liquid and lyophilized formulations.

Process Development & Optimization

Applying over 20 years of process development experience our development, optimization and manufacturing teams collaborate together to develop quality, commercially viable processes. We can ensure seamless scale up through to commercial launch.

Clinical to Commercial Manufacturing

We have a proven track record in cGMP manufacturing a wide range of molecules, from straightforward to very complex modalities. Using a diverse range of expertise in technology transfer, PPQ, regulatory support, scaling and clinical to commercial manufacturing of biopharmaceutical products, we create tailored solutions for your program.

Locations

We continue to invest in our state-of-the-art facilities in the US and the UK.

San Diego, CA, USA

6325 Lusk Blvd.
San Diego,
CA 92121
USA
+1 858-550-4094

San Diego, CA, USA

2858 Loker Ave E. Suite 100
Carlsbad,
CA 92010
USA
Explore San Diego
+1 858-550-4094

San Diego, CA, USA

11425 Sorrento Valley Rd.
San Diego,
CA 92121
USA
+1 858-550-4094

Bristol, PA, USA

360 George Patterson Blvd.
Bristol
PA,19007
USA
Explore
+1 215-788-3603

Cambridge, UK

Babraham Research Campus,
Cambridge,
CB22 3AT
United Kingdom
Explore
+44 1223 903498