Platform Approach for Identifying the Most Functional and Developable Bispecific T Cell Engager

Access our latest poster from AAPS PharmSci360 entitled, “Platform Approach for Identifying the Most Functional and Developable Bispecific T Cell Engager”

The purpose of this study was to evaluate a platform for optimal bispecific design and selection using two functionalities, a cancer target – anti CD19, T cell recruiter – anti-CD. Key learnings from this project include the importance of gaining high purity from simple purifications and the potential problems with reformatting into a single chain Fv format.

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Poster authors include: Tom Cornell, Tim wood, Dawn Bembridge, Chris Sayer, Evert Bokma, Patrick Lynch, Galia Konfortova, Cherry Chui, Mariarosaria Cerchia, Farnoush Masoudzadeh, Katie Welch, Erika Kovacs, Arron Hearn, Rob Holgate &