Bioconjugate & ADC Complex Chemistry

• Complex molecules including cytotoxins, payloads, active pharmaceutical ingredients (APIs), high potency active pharmaceutical ingredients (HPAPIs) and their metabolites, process chemistry impurities, and fine chemicals
• State-of-the-art methodologies, including asymmetric synthesis and modern catalytic methods, for design and optimization of synthetic routes for the preparation of complex molecules (e.g., cytotoxins, novel payloads, payload-linker constructs, API, and HPAPI).
• Current synthetic routes or development of new and efficient routes for the preparation of biologically active and complex molecules including peptides, oligonucleotides, nanoparticles, carbohydrates, and polymers

The advancement of antibody-drug conjugates (ADCs) and other bioconjugates requires a high level of specialized chemistry knowledge. This needs to encompass the design and synthesis of intricate molecules, including cytotoxins and diverse linker payloads. At Abzena, we are proficient in complex chemistry, offering comprehensive support throughout the entire ADC development pathway. Our scientific experts can support your program from discovery and design to development and clinical manufacturing.

Discover more about our complex chemistry and ADC expertise by downloading our info sheet today.