Biologics Discovery to Lead Candidate

Our biologic discovery-to-lead candidate selection process selects a single drug candidate from a group of potential leads based on a variety of factors, including:

• Specificity: Ensuring your molecule binds with high specificity to its intended target
• Functionality: Characterizing the functionality of your molecule against different variants and competitor drugs, where relevant
• Safety: With our experience in assessing thousands of molecules we determine the least immunogenic lead candidates for clinical evaluation to reduce the potential for side effects, toxicity, and other adverse reactions
• Manufacturability: How easy it would be to synthesize the drug on a large scale

We have worked with hundreds of biologic candidates and have the experience to help inform your approach with a commitment to quality excellence. We can reduce project timescales by applying a parallel multiparametric evaluation approach covering specificity, functionality, safety and manufacturability.

Our developability assessment process delivers the right set of bioassays and analytics to assess the developability of your drug candidates. This process ensures the candidates that you take forward have reduced liabilities and a de-risked development path.