Why Abzena?
Our focused approach.
To balance the scales more favorably, and mitigate some of the biggest risks in drug development, it is essential to gather as much information about a drug candidate early on to make better, more informed decisions further down the line. This is where the idea of ‘developability‘ comes in. Developability helps balance the scales of an ideal drug candidate vs the challenges of reality.
Balancing everything we would want in a perfect candidate vs. everything we face in reality.
How do Abzena allow you to start smart and finish fast? Read more below or contact our team of experts today to learn more about our ‘developability’ process.
Average cost
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(Sun D et al. (2022) Acta Pharm Sin B. Jul;12(7):3049-3062)
Can we make the drug as a stable compound in the required form and quality to treat patients?
Can we make the drug at scale, with an acceptable cost, within acceptable timeframe, with enough doses to treat the patient population?
Does the drug do what we expected it to do – is there a predictable mechanism of action?
Does the drug have the desired efficacy?
Is the drug safe for the target patient population?
By asking those simple questions, “Can we make it?” and “Does it work?” right from the start, we can start to whittle down candidates from hundreds to a handful. From there, we can keep refining the selection criteria, continually derisking a project and moving closer to that ideal drug.
Hit generation followed by high throughput in silico and in vitro screening to screen out candidates with undesirable properties.
Candidates are designed and engineered to remove undesirable properties and introduce desirable properties.
Detailed biological and biophysical characterization of a small panel of molecules in order to select a lead candidate for progression.
Comprehensive understanding of a single candidate and capability to develop, manufacture and deliver your drug for both clinical and commercial scale.
Now you know more about what goes into the developability process at Abzena, what exactly can you get? Well, we offer both pre-defined and tailored work packages so you can get exactly what your project needs.
To find out more about our developability packages please get in touch with our experts today.
Get in touch and let’s work together to move medicine forward faster.