Bioconjugate & ADC Complex Chemistry

Tailored solutions, reliably delivered.

We design and improve existing synthetic routes for complex chemicals by proposing and executing more efficient and innovative approaches.

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Our team of experts apply state-of-the-art methodologies to synthesize complex molecules including payloads, preclinical drug candidates, reference compounds, and process impurities.

Abzena’s Chemistry facility in Bristol, PA, USA, tackles challenging synthetic and medicinal targets. Our highly experienced chemists have been trained in someof the world’s top academic research labs; most have PhD level degrees and extensive R&D experiences in the pharmaceutical industry.

Our capabilities include expertise in:

  • Complex molecules including cytotoxins, payloads, active pharmaceutical ingredients (APIs), high potency active pharmaceutical ingredients (HPAPIs) and their metabolites, process chemistry impurities, and fine chemicals
  • State-of-the-art methodologies, including asymmetric synthesis and modern catalytic methods, for design and optimization of synthetic routes for the preparation of complex molecules (e.g., cytotoxins, novel payloads, payload-linker constructs, API, and HPAPI).
  • Current synthetic routes or development of new and efficient routes for the preparation of biologically active and complex molecules including peptides, oligonucleotides, nanoparticles, carbohydrates, and polymers

Let’s move medicine forward.

The treatments you’re developing right now can make a real difference for human health. Let us use our industry-leading expertise in developing and manufacturing ADCs, bioconjugates, and linker payloads to further your essential efforts.