AbZelectPRO™: Enhanced Cell Line Development - Abzena

Ready to move your medicine forward?
Discover Abzena.

Welcome to the leading CDMO + CRO for biologics & bioconjugates including ADCs, AOCs, RDCs.

A history of successfully moving medicine forward.

20+

years of end-to-end complex biologics and bioconjugation services experience

2000+

conjugates developed for critical assays, and lead candidate selections with over 400 ADCs produced

50+

bioconjugation programs scaled up to produce multi gram batches

It is never too early or late to research your biologic drug development options. Opportunity is right here. Who can you count on to de-risk and move your medicine forward with a focus on quality and a high-level of expertise? Abzena offer best-in-class bioconjugate and biologic CDMO + CRO services. Along with a highly detailed and personalized experience.

Abzena provides fully integrated early R&D, through commercial capabilities underpinned by rapid high-quality, and trusted data which drives development. We offer streamlined regulatory support that is tailored to your program. We are as committed to the downstream success and quality of your drug as you are. Abzena have the know-how and capacity to move your medicine forward.

 

What sets Abzena apart?


Abzena have a focused approach to get it right from the start.

Find out what sets us apart by downloading our brochure or reading more below.

Access to Genuine Scientific & Technical Experts

We have over 20 years of experience in delivering solutions at each stage of the development lifecycle from early-stage research and discovery, through lead candidate selection, and onward into process development and GMP manufacture.

Unlike most other service providers, we can provide technical and scientific support that truly spans early-stage research through process development and GMP manufacturing under a single organization to better ensure that the TPP can be achieved. Our global scientific teams have extensive experience in overcoming some of the most challenging and complex biologic and bioconjugate programs, making us the perfect partner for novel and disruptive technologies that other biopharmaceutical CDMOs may shy away from.

Proactive Problem Solving to Ensure Downstream Success

Our experienced team is focused on getting it right from the start. We identify and address challenges early in drug design to better ensure downstream clinical and commercial success. We also have expertise in fixing and optimizing drugs in later stage development to rescue them from the drug development graveyard.

Diverse & Interconnected Expertise Under a Single Organization

With capabilities ranging from bioassays to cell line development, bioconjugation and clinical and commercial manufacturing, all under one organization, we can reduce the white space in the development path, which ultimately minimizes risk, reduces costs and accelerates timelines for our customers.

As an integrated service provider, we accelerate timelines through the ease of technical and materials transfer, and improved scheduling. Better workflows and processes can also be attained through improved knowledge transfer between internal multidisciplinary experts and the development of a deep understanding of the drug as it progresses from target to lead selection and process development and manufacture.

Driven by Innovation to Streamline Development

Our team is always seeking new ways to innovate and streamline development for our customers. Our extensive scientific capabilities and proprietary solutions like EpiScreen® 2.0, Composite Proteins™, Composite Human Antibodies™, AbZelectPRO™, ThioBridge™, and LabZient™ are designed to give your program the best chance of clinical and commercial success.

  • EpiScreen® 2.0 — an extensive suite of bioinformatic and primary human cell-based assays for immunogenicity assessment to inform of potential safety and efficacy risks in the clinic.
  • Composite Human Antibody™ — a platform used for designing safer, more effective, humanized antibodies.
  • Composite Proteins™ — a deimmunization technology that designs safer and more effective therapeutic proteins, devoid of human T cell epitopes, to minimize potential immunogenicity in patients without compromising activity.
  • AbZelectPRO™ — high-yielding cell line development (CLD) platform for accelerating the generation of production cell lines for manufacture of antibodies and recombinant proteins.
  • ThioBridge™ — a next-generation conjugation linker technology proven to enhance ADC development by overcoming issues with existing technologies to improve stability, potency, and efficacy.
  • LabZient™ — our analytical platform that combines predictive in-silico evaluation with laboratory methods to de-risk the application of platform analytical procedures and expedites the pathway to IND.

We understand your challenges

Are you faced with

Looking for a proven biologics CDMO partner for a new or existing development program?

Looking to collaborate, reduce risk, and accelerate timelines?

Researching a more flexible and adaptive tech transfer approach?

Trust isn’t given, it’s earned.

That’s why we’re proud to have over 20 years of complex biologics and bioconjugation expertise, completing many projects for customers around the world.

Whatever your biologic development challenge, you can be confident that Abzena are ready to help move your medicine forward.

Contact Us

Discover our stable cell line development services

Gain actionable insights into integrating innovative cell line development technologies, de-risking strategies, and efficient development approaches to maximize the success of your biologics program.

Watch Abzena’s Brett Verstak, Director of Cell Line Development excerpt on AbZelectPRO™, our enhanced CHO cell line development platform, and request full access to the on-demand webinar recording by clicking the button below.

Let's work together to move medicine forward today.