Utilizing Live Cell Imaging for Better Lead Selection of Biologics and Bioconjugates

Most in vitro assays weren’t designed with bioconjugates in mind. The biology that makes ADCs, AOCs  and engineered biologics so powerful — cleavable linkers, bystander killing, immune-mediated mechanisms — is often the same biology that conventional cell-based assays fail to capture.

When early screening models lack the cellular complexity and human fidelity to reflect those mechanisms, you’re selecting candidates against an incomplete picture.  Access our on-demand webinar to hear from our experts, Abzena’s Robert J Francis PhD, and Kirsty McBain from Sartorius, as they explore how live-cell imaging can address this directly — covering co-culture and spheroid systems, immune cell integration, and what that means in practice for ADC and bispecific programs.

If lead selection is a bottleneck in your pipeline, this one’s worth an hour.

You will learn from this webinar:

  • Importance of holistic assay strategies for complex biologic development
  • Pushing the boundaries of live-cell imaging with the Incucyte®
  • Using co-culture and spheroid cultures in the presence and absence of immune cells
  • Case study insights for ADC and bispecific programs

 Access  the Webinar

 

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