Assessing Effector Function in Biologics

What is effector function & why is it important? Antibody effector function is an important part of the immune response and forms an essential link between innate and adaptive immunity.

Understanding the mode of action of a drug candidate is essential for every drug development program. Abzena has developed a comprehensive suite of assays to support the characterization of the Fc-mediated activity of antibodies, Fc fusions or ADC products. Each assay can be tailored to the specific requirements of your project and our team of experts will work with you to provide solutions to suit your specific needs, considering aspects such as mode of action, assay sensitivity, complexity and regulatory requirements.

In this info sheet, our experts detail key aspects for developing successful Fc effector functional assays and discuss the benefits and challenges of a panel of assay formats for different purposes. They provide options for choosing the most suitable target cell lines, effector cells, and appropriate controls.

In summary, download our info sheet to learn about:

• What is Effector Function & Why is it Important?
• Types of Effector Function
• How to Select the Right Assay?
• Quality Data Generation
• Effector Function & Fc Engineering

Download Info Sheet