Incucyte User Group Meeting 2025: Utilizing Live Cell Imaging for Better Lead Selection of Biologics and Bioconjugates

Abzena’s Sr. Director of Bioassay, Erika Kovacs, presented on behalf of our Cambridge bioassay team at the UK Incucyte® User Group Meeting 2025 on “Utilizing Live Cell Imaging for Better Lead Selection of Biologics & Bioconjugates,” which was hosted on Wednesday, September 17, 2025 in Cambridge, UK.

Her presentation walked through three in-depth case studies:
1. Assessing the Functionality and Safety of Bispecifics
2. Modelling Complex Cell Environments In vitro for ADC Lead Selection
3. Assessment of Payload and Immune-Mediated Killing in a Single Assay

These case studies examined how live cell imaging could be leveraged to capture the fundamental characteristics of successful drug design and enhance the likelihood of obtaining a successful lead bispecific or ADC to progress onward toward the clinic.

Click Here to Access the Presentation Slides

Special thanks to our Cambridge team: Thomas Cornell, Timothy Wood, Katie Welch, Rob Holgate, Grant Harradence, Robert J. Francis, Johanna Midelet, Yasmin Noble, Rosa Gonzalez-Serrano

This year’s meeting will be held at the prestigious AstraZeneca Discovery Centre (DISC), providing the perfect setting for networking, scientific exchange, and exploration of the latest developments in Live-Cell Imaging.  The annual Incucyte® User Group Meeting brings together users from across the UK for a day of cutting-edge science, collaboration, and innovation.

For more information, visit the events website.

Interested in learning more about Abzena’s extensive live cell imaging capabilities?  We recently presented a poster entitled ‘Application of Real-Time Live Cell Imaging in the Development of Antibody-Drug Conjugates’. This poster shows how Abzena provides live cell imaging expertise within our diverse range of offerings in developing and progressing antibody-drug conjugates (ADCs) and other complex biologics. Click here to access the poster. 

Abzena’s Bioassay Capabilities

At Abzena, we have decades of expertise in delivering a range of reliable, early bioassays. These have been proven to help our customers streamline and de-risk their complex biologic or bioconjugate development programs.

We lead with an adaptable approach. We shorten the discovery phase, getting your product from bench-to-bedside faster, and with greater success. Our mission is to move medicine forward, ensuring your overall success in delivering vital medicines to patients.

We offer comprehensive bioassay services and solutions for: antibodies, conjugates, multi-specifics, fusions, fragments and agonist / antagonist activities.

Our unique approach focuses on developing phase-appropriate assays that are tailored to your program, giving you tools to make effective decisions during your drug development journey to IND and beyond.

Our broad array of bioassay platforms includes:

  • Luminescence, fluorescence, absorbance plate-based assays
  • Biacore™
  • Flow cytometry
  • Incucyte® live cell imaging (and other microscopy techniques)
  • Cytokine analysis (Luminex®, FluoroSpot

Click here to learn more

 

 

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