Senior Scientist - Abzena

Senior Scientist

Location: Cambridge, UK
Area: Analytics

We have a vacancy at Senior Scientist level for an experienced protein biochemist to join our busy Analytics group in Cambridge (UK).  In this lab-based role you will be working in a fast-paced and supportive environment as part of a multidisciplinary team, to provide innovative solutions to support client-facing drug development projects.

Abzena provides the most complete set of solutions in integrated early discovery to mid-phase biotherapeutic and ADC drug development services in the pharmaceutical industry. Working with a varied range of customers from academic groups, small biotech and big pharma and on a diverse range of drug types from antibodies, fusion proteins and bioconjugates, Abzena supports the development and manufacture of better treatments for patients. As a testimony of its outstanding expertise and quality of its services in bioconjugates early development, Abzena won the best CRO award at the World ADC conference in 2020.

The Analytics group in Abzena Cambridge (UK) provides analytical solutions and developments concerning all areas of research in Abzena, such antibody and ADC characterisation, determination of critical quality attributes of biopharmaceuticals, stability indicating assays or protein-formulation screening, immuno-peptidomics and cellular proteomics. To support Abzena’s biotherapeutic research activities the Analytics lab in Cambridge is equipped with state-of-the-art instrumentation including UPLC chromatography, microfluidics capillary electrophoresis, dynamic light scattering platforms, and high-resolution Q-TOF, high sensitivity TOF, and Orbitrap mass spectrometers.

Ideally, you will have a PhD or MSc (or a lower level of qualification and relevant experience) in Protein Biochemistry/Chemistry or related science discipline with strong laboratory skills and experience in an industrial or commercial environment. Relevant skills required include an in-depth understanding of protein analytics coupled with practical research experience of characterisation techniques such as column chromatography (HIC, SEC, IEX), UV-Vis spectrophotometry, microfluidics (CE-SDS, CZE) and LC-MS. As a confident IT user, you will be familiar with MS Office, and specialist software including Chromeleon, Unifi, or MassLynx. You will have a good understanding of protein analytics and its application in biotherapeutic drug development.

You will be able to work both independently and as part of a team, have good planning and organising skills. In addition, you will have a high level of attention to detail and be able to identify and analyse and resolve routine and complex problems. You will be proactive and independent, with a high level of autonomy and initiative. You will demonstrate an ability to communicate clearly both orally and in writing, keeping team and management informed. You will contribute to the group development effort undertaking advanced research, managing client projects and interactions in a professional manner.

In return, we can offer you a competitive salary and benefits package and a collaborative, varied and challenging environment where you will be encouraged to step outside your comfort zone and develop your career.

Job description

  • To be responsible for day-to-day management of studies
  • To be responsible for delivery of key/discrete work packages
  • To design, co-ordinate and perform multiple experiments
  • To independently undertake advanced research, performing complex science without supervision
  • To investigate new techniques under direction
  • To manage own work schedule to ensure tasks are met within the expected timeframe
  • To analyse and interpret own data and those of junior staff
  • To prepare data for, contribute to and lead the drafting of reports and presentations
  • To contribute to and lead internal and client meetings
  • To contribute to writing and reviewing Quality and Controlled documents
  • To undertake any other duties relevant to the position and level
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