FC Binding and Function Assays

Fc-mediated effector functions may play a role in the mechanism of action of an antibody or an antibody drug conjugate (ADC) and have an impact on the product safety and efficacy.

For these reasons, both EMEA and FDA guidelines recommend to analyze Fc functions in detail, including binding to Fc receptors and Fc-mediated cytotoxicity such as ADCC and CDC.

Abzena offers a complete solution to support the characterization of the Fc-mediated activity of your antibody or ADC product.

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